KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNMT
All Species:
24.24
Human Site:
S185
Identified Species:
53.33
UniProt:
Q14749
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14749
NP_061833.1
295
32742
S185
R
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089876
295
32693
S185
R
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
Dog
Lupus familis
XP_532140
295
32695
S185
R
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXF8
293
32657
S183
R
N
Y
D
Y
I
L
S
T
G
C
A
P
P
G
Rat
Rattus norvegicus
P13255
293
32531
S183
R
N
Y
D
Y
I
L
S
T
G
C
A
P
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508790
588
65253
S478
R
N
Y
D
H
I
L
S
T
G
C
A
P
P
G
Chicken
Gallus gallus
XP_001232829
531
58160
A421
R
N
Y
D
H
I
L
A
T
G
C
A
P
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997981
294
33227
E184
R
N
Y
D
Y
I
I
E
T
G
Q
V
P
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650223
289
32665
H180
G
G
V
L
L
I
D
H
R
N
Y
D
N
I
L
Honey Bee
Apis mellifera
XP_625210
292
33740
I183
H
R
N
Y
D
F
I
I
E
T
G
N
I
P
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784229
290
32784
S181
I
D
H
R
N
L
D
S
M
L
D
H
G
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
96.2
N.A.
91.8
91.5
N.A.
39.6
38.9
N.A.
72.5
N.A.
56.9
57.9
N.A.
36.6
Protein Similarity:
100
N.A.
99.6
97.2
N.A.
95.5
95.9
N.A.
45.2
47
N.A.
83.3
N.A.
72.1
72.1
N.A.
53.2
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
60
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
N.A.
73.3
N.A.
6.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
64
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% C
% Asp:
0
10
0
73
10
0
19
0
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
73
10
0
10
0
73
% G
% His:
10
0
10
0
46
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
82
19
10
0
0
0
0
10
19
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
10
10
64
0
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
73
10
0
10
0
0
0
0
10
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
73
73
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% Q
% Arg:
73
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
73
10
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
73
10
28
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _